Gene Therapy Essay Example

Gene Therapy Essay Example Gene Therapy Essay Gene Therapy Essay Gene Therapy What is it? If genes dont produce the right protein or dont produce it correctly a person can have a genetic disorder. Gene therapy is an experimental technique that involves the transfer of a working copy of a gene into a cell to repair or replace a faulty gene so it is able to produce functioning proteins again. There are several approaches. The most common one is to insert a normal gene to replace the non-functional gene. Another approach is to swap a non-functional gene with a normal gene or the faulty ene could be repaired through selective mutations. Also genes can be switched on and off to a certain degree. How does gene therapy work? A carrier gene, called a Vector brings the normal gene into the target cell. Currently a virus is commonly used for that. The virus infects the target area with the healthy gene and so the cells can produce functioning proteins again. The genes can also be directly introduced to the target cells; this can only used in some tissues though. Also an artificial sphere, called Liposome, can be used which carries the DNA and is capable of passing the DNA through the target cells membrane. Another way is to chemically link the DNA to a molecule that will bind to specific cell receptors. Then the DNA will be passed into the target cell. This though seems to be less effective than other options. Advantages: has the potential to restore health to many who are suffering with the disease Disadvantages: controversy surrounding the medical treatment relative newness of the technology :

About McLaughlin v. State of Florida in 1964

About McLaughlin v. State of Florida in 1964 Background: An interracial black-white couple, identified only as McLaughlin in the ruling, was prohibited from marrying under Florida law. Like same-sex couples prohibited from marrying today, they chose to live together anywayand were convicted under Florida Statute 798.05, which reads: Any negro man and white woman, or any white man and negro woman, who are not married to each other, who shall habitually live in and occupy in the nighttime the same room shall each be punished by imprisonment not exceeding twelve months, or by fine not exceeding five hundred dollars. Fast Facts: McLaughlin v. Florida Case Argued: Oct. 13-14, 1964Decision Issued: Dec. 7, 1964Petitioner: McLaughlinRespondent: State of FloridaKey Question: Can an interracial couple be subjected to race-contingent fornication charges?Majority Decision: White, Warren, Black, Clark, Brennan, Goldberg, Harlan, Stewart, DouglasDissenting: NoneRuling: The Supreme Court ruled that the Florida criminal statute that prohibits an unmarried interracial couple from habitually living in and occupying the same room in the night-time denies the equal protection of the laws guaranteed by the 14th Amendment, and is thus unconstitutional. The Central Question: Can an interracial couple be subjected to race-contingent fornication charges? Relevant Constitutional Text: The Fourteenth Amendment, which reads in part: No State shall make or enforce any law which shall abridge the privileges or immunities of citizens of the United States; nor shall any State deprive any person of life, liberty, or property, without due process of law; nor deny to any person within its jurisdiction the equal protection of the laws. The Courts Ruling: In a unanimous 9-0 ruling, the Court struck down 798.05 on grounds that it violates the Fourteenth Amendment. The Court also potentially opened the door to full legalization of interracial marriage by remarking that the 1883 Pace v. Alabama represents a limited view of the Equal Protection Clause which has not withstood analysis in the subsequent decisions of this Court. Justice Harlans Concurrence: Justice Marshall Harlan concurred with the unanimous ruling but expressed some frustration with the fact that Floridas blatantly discriminatory law banning interracial marriage was not directly addressed. Justice Stewarts Concurrence: Justice Potter Stewart, joined by Justice William O. Douglas, joined in the 9-0 ruling but expressed firm disagreement in principle with its implicit statement that racially discriminatory laws might be constitutional under certain circumstances if they serve some overriding statutory purpose. I think it is simply not possible, Justice Stewart wrote, for a state law to be valid under our Constitution which makes the criminality of an act depend upon the race of the actor. Aftermath: The case put an end to laws banning interracial relationships as a whole, but not to laws banning interracial marriage. That would come three years later in the landmark Loving v. Virginia (1967) case.

About McLaughlin v. State of Florida in 1964

About McLaughlin v. State of Florida in 1964 Background: An interracial black-white couple, identified only as McLaughlin in the ruling, was prohibited from marrying under Florida law. Like same-sex couples prohibited from marrying today, they chose to live together anywayand were convicted under Florida Statute 798.05, which reads: Any negro man and white woman, or any white man and negro woman, who are not married to each other, who shall habitually live in and occupy in the nighttime the same room shall each be punished by imprisonment not exceeding twelve months, or by fine not exceeding five hundred dollars. Fast Facts: McLaughlin v. Florida Case Argued: Oct. 13-14, 1964Decision Issued: Dec. 7, 1964Petitioner: McLaughlinRespondent: State of FloridaKey Question: Can an interracial couple be subjected to race-contingent fornication charges?Majority Decision: White, Warren, Black, Clark, Brennan, Goldberg, Harlan, Stewart, DouglasDissenting: NoneRuling: The Supreme Court ruled that the Florida criminal statute that prohibits an unmarried interracial couple from habitually living in and occupying the same room in the night-time denies the equal protection of the laws guaranteed by the 14th Amendment, and is thus unconstitutional. The Central Question: Can an interracial couple be subjected to race-contingent fornication charges? Relevant Constitutional Text: The Fourteenth Amendment, which reads in part: No State shall make or enforce any law which shall abridge the privileges or immunities of citizens of the United States; nor shall any State deprive any person of life, liberty, or property, without due process of law; nor deny to any person within its jurisdiction the equal protection of the laws. The Courts Ruling: In a unanimous 9-0 ruling, the Court struck down 798.05 on grounds that it violates the Fourteenth Amendment. The Court also potentially opened the door to full legalization of interracial marriage by remarking that the 1883 Pace v. Alabama represents a limited view of the Equal Protection Clause which has not withstood analysis in the subsequent decisions of this Court. Justice Harlans Concurrence: Justice Marshall Harlan concurred with the unanimous ruling but expressed some frustration with the fact that Floridas blatantly discriminatory law banning interracial marriage was not directly addressed. Justice Stewarts Concurrence: Justice Potter Stewart, joined by Justice William O. Douglas, joined in the 9-0 ruling but expressed firm disagreement in principle with its implicit statement that racially discriminatory laws might be constitutional under certain circumstances if they serve some overriding statutory purpose. I think it is simply not possible, Justice Stewart wrote, for a state law to be valid under our Constitution which makes the criminality of an act depend upon the race of the actor. Aftermath: The case put an end to laws banning interracial relationships as a whole, but not to laws banning interracial marriage. That would come three years later in the landmark Loving v. Virginia (1967) case.

About McLaughlin v. State of Florida in 1964

About McLaughlin v. State of Florida in 1964 Background: An interracial black-white couple, identified only as McLaughlin in the ruling, was prohibited from marrying under Florida law. Like same-sex couples prohibited from marrying today, they chose to live together anywayand were convicted under Florida Statute 798.05, which reads: Any negro man and white woman, or any white man and negro woman, who are not married to each other, who shall habitually live in and occupy in the nighttime the same room shall each be punished by imprisonment not exceeding twelve months, or by fine not exceeding five hundred dollars. Fast Facts: McLaughlin v. Florida Case Argued: Oct. 13-14, 1964Decision Issued: Dec. 7, 1964Petitioner: McLaughlinRespondent: State of FloridaKey Question: Can an interracial couple be subjected to race-contingent fornication charges?Majority Decision: White, Warren, Black, Clark, Brennan, Goldberg, Harlan, Stewart, DouglasDissenting: NoneRuling: The Supreme Court ruled that the Florida criminal statute that prohibits an unmarried interracial couple from habitually living in and occupying the same room in the night-time denies the equal protection of the laws guaranteed by the 14th Amendment, and is thus unconstitutional. The Central Question: Can an interracial couple be subjected to race-contingent fornication charges? Relevant Constitutional Text: The Fourteenth Amendment, which reads in part: No State shall make or enforce any law which shall abridge the privileges or immunities of citizens of the United States; nor shall any State deprive any person of life, liberty, or property, without due process of law; nor deny to any person within its jurisdiction the equal protection of the laws. The Courts Ruling: In a unanimous 9-0 ruling, the Court struck down 798.05 on grounds that it violates the Fourteenth Amendment. The Court also potentially opened the door to full legalization of interracial marriage by remarking that the 1883 Pace v. Alabama represents a limited view of the Equal Protection Clause which has not withstood analysis in the subsequent decisions of this Court. Justice Harlans Concurrence: Justice Marshall Harlan concurred with the unanimous ruling but expressed some frustration with the fact that Floridas blatantly discriminatory law banning interracial marriage was not directly addressed. Justice Stewarts Concurrence: Justice Potter Stewart, joined by Justice William O. Douglas, joined in the 9-0 ruling but expressed firm disagreement in principle with its implicit statement that racially discriminatory laws might be constitutional under certain circumstances if they serve some overriding statutory purpose. I think it is simply not possible, Justice Stewart wrote, for a state law to be valid under our Constitution which makes the criminality of an act depend upon the race of the actor. Aftermath: The case put an end to laws banning interracial relationships as a whole, but not to laws banning interracial marriage. That would come three years later in the landmark Loving v. Virginia (1967) case.

Hershey's Sweet Mission Term Paper Example | Topics and Well Written Essays - 1000 words

Hershey's Sweet Mission - Term Paper Example This paper analyses the given case; Hershey’s Sweet Mission in terms of relevant human resource management theories. Recommendation for the redesign of Hershey’s performance management system to appeal to the diverse groups that it employs According to Lindbom (2007), â€Å"the foundation for effective performance management is the importance of including people development as part of the long-term strategic plan of an organization† (p.103). The contributions of the older employees are as important as the contributions of the younger employees. Hershey’s performance management system is giving more focus to the interests of younger employees. The case says that Hershey’s performance management system is appealing to the younger generations’ eagerness for challenge, autonomy, and results. At the same time, it says nothing about the contributions of baby boomers or old age employees. The contributions of young and elder employees are equally im portant for an organization. Hershey should realise this fact very well and should give more considerations to the contributions of the elder employees also. It should be noted that the fresh ideas brought by the younger employees need some fine-tuning from the experienced ones before its implementation. Knowledge management theory says that an organization’s performance is heavily dependent on the knowledge of its workforce. Experienced workers definitely have knowledge that is more practical even though fresh workers may have more theoretical knowledge. Both theory and practice are important for an organization like Hershey. So, Hershey should recognize the needs of the experienced workers as important as that of the fresh workers. Armstrong-Stassen and Templer (2005) argue that, although there are many training programs for older worker, it is important to take into account the experience of the older employees and redesign the training and the method accordingly (p.57). M odern organizations like Hershey often gives more emphasize to the needs of younger employees while formulating training programs. Moreover, these training programs often cater the needs of local employees. Since Hershey employs employees from different parts of the world, its training programs should give more focus to the needs of the diverse workforce. Lee (2005) stresses the importance of future-oriented performance management and evaluation system (p.53). Hershey should redefine its performance management system by giving more focus to future rather than present. How I would interpret the values that Hershey embraces in relation to my role, if I was a Hershey’s employee With regard to employees, Hershey’s mission statement says that the mission involves â€Å"winning with an aligned and empowered organization . . . while having fun.† Moreover, â€Å"Aligned† employees should share values, be clear about how their work contributes to the organizationà ¢â‚¬â„¢s mission, collaborate effectively, and be selected, equipped, and rewarded for meeting company objectives. If I was an employee in Hershey, I should work in accordance with the mission statement of Hershey. In other words, I should make sure that all the activities performed by me are in line with the vision and mission statement of Hershey. I should give more focus to the company objectives instead of my own personal preferences. For example, If Hershey asks me to

An Outline History of the World Essay Example | Topics and Well Written Essays - 1250 words

An Outline History of the World - Essay Example It is possible that this pagi consisted of specific clans which later migrated and got divided into large families which were headed by the father, the paterfamilias. Each of these, in turn, had acquired possession of slaves of both genders, called famuli, in the beginning from the native land and later from other regions. The slaves, like women and children, were excluded from the participatory realm of governance in the polis. Individual rights were restricted to the adult male community, in a similar manner to the Greek system, on which the early Roman civilization has borrowed a lot. However, as Boris Piotrovsky points out, there is a different version to the legend of the founders of Rome, Romulus, and Remus, as â€Å"they were the sons of a slave woman and the hearth deity†. 1 Hence the history of ancient Rome, the rise of its Empire, glorious battles and its eventual fall is replete with references to slaves, predominantly from the perspective of the dominant community but interspersed with events that were the first instances of slave revolts which led to legendary epochs. Tacitus’ Annals presents a case of the city prefect Padanius Secundus’s murder by his slaves. The general sentiment regarding the case was to execute all the slaves who were employed in his house. There was a riot in which some members of the Senate were concerned about the cruelty involved in such a decision, taking into account the fact that the slaves included many women and children who were ostensibly innocent. However, the strong arguments made by Gaius Cassius in support of the decision to execute all the slaves won over this concern by some senators to â€Å"eliminate excessive cruelty†2. According to him, â€Å"if we must die, we will not be unavenged nor will the guilty survive†.  

Letter Written By MLK From Birmingham City Jail, Alabama :: essays research papers

My Dear Fellow Clergymen: While confined here in the Birmingham city jail, I came across your recent statement calling my present activities "unwise and untimely." Seldom do I pause to answer criticism of my work and ideas. If I sought to answer all the criticisms that cross my desk, my secretaries would have little time for anything other than such correspondence in the course of the day, and I would have no time for constructive work. But since I feel that you are men of genuine good will and that your criticisms are sincerely set forth, I want to try to answer your statements in what I hope will be patient and reasonable terms. I think I should indicate why I am here In Birmingham, since you have been influenced by the view which argues against "outsiders coming in." I have the honor of serving as president of the Southern Christian Leadership Conference, an organization operating in every southern state, with headquarters in Atlanta, Georgia. We have some eighty-five affiliated organizations across the South, and one of them is the Alabama Christian Movement for Human Rights. Frequently we share staff, educational and financial resources with our affiliates. Several months ago the affiliate here in Birmingham asked us to be on call to engage in a nonviolent direct-action program if such were deemed necessary. We readily consented, and when the hour came we lived up to our promise. So I, along with several members of my staff, am here because I was invited here I am here because I have organizational ties here. But more basically, I am in Birmingham because injustice is here. Just as the prophets of the eighth century B.C. left their villages and carried their "thus saith the Lord" far beyond the boundaries of their home towns, and just as the Apostle Paul left his village of Tarsus and carried the gospel of Jesus Christ to the far corners of the Greco-Roman world, so am I compelled to carry the gospel of freedom beyond my own home town. Like Paul, I must constantly respond to the Macedonian call for aid. Moreover, I am cognizant of the interrelatedness of all communities and states. I cannot sit idly by in Atlanta and not be concerned about what happens in Birmingham. Injustice anywhere is a threat to justice everywhere. We are caught in an inescapable network of mutuality, tied in a single garment of destiny.